Post-exposure therapy in mice against experimental rabies: a single injection of DNA vaccine is as effective as five injections of cell culture-derived vaccine

Genetic immunization is a simple method for eliciting an immune response

De‐chu C. Tang, Michael J. DeVit, Stephen Albert Johnston · Nature · 1992 · 1.5K citations

Life Sciences, Genetics, Immunology +8

CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma.

Dennis M. Klinman, Ae‐Kyung Yi, Serge L. Beaucage et al. · Proceedings of the National Academy of Sciences · 1996 · 1.5K citations

Life Sciences, Immunology, Microbiology +17

Immunostimulatory DNA Sequences Necessary for Effective Intradermal Gene Immunization

Yukio Sato, Mark Roman, Helen Tighe et al. · Science · 1996 · 1.1K citations

Life Sciences, Biotechnology, Immunology +17

Bacterial DNA Induces Murine Interferon-γ Production by Stimulation of Interleukin-12 and Tumor Necrosis Factor-α

Melissa D. Halpern, Roger Kurlander, David S. Pisetsky · Cellular Immunology · 1996 · 395 citations

Life Sciences, Immunology, Microbiology +12

Vaccination with a Plasmid Vector Carrying the Rabies Virus Glycoprotein Gene Induces Protective Immunity against Rabies Virus

Zhi Quan Xiang, Steven L. Spitalnik, Minh H. Tran et al. · Virology · 1994 · 392 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17