Highly Active Antiretroviral Treatment (HAART) and Health-Related Quality of Life in Naive and Pretreated HIV-Infected Patients

Abstract

After 3 months of therapy with a HAART regimen, including two nucleoside analogues plus indinavir, naive patients presented a greater virological response but no significant differences in changes in HR-QOL when compared to pretreated patients. Both naive patients and patients previously treated with two nucleoside analogues showed improvement in clinical variables and in HR-QOL after this period of time.