Riluzole specifically blocks inactivated Na channels in myelinated nerve fibre

Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction.

Bertil Hille · The Journal of General Physiology · 1977 · 1.8K citations · Full text

Local Pharmacology, Anesthetic Mechanism, Pharmacotherapy +19

A new voltage clamp method for Ranvier nodes

Wolfgang Nonner · Pflügers Archiv - European Journal of Physiology · 1969 · 246 citations

Numerical Analysis, Electrical Engineering, Engineering +4

Voltage clamp analysis of the inhibitory actions of diphenylhydantoin and carbamazepine on voltage-sensitive sodium channels in neuroblastoma cells.

Max Willow, Tohru Gonoi, William A. Catterall · Molecular Pharmacology · 1985 · 230 citations

Quantitative description of sodium currents in myelinated nerve fibres of <i>Xenopus laevis</i>

B. Frankenhaeuser · The Journal of Physiology · 1960 · 222 citations · Full text

Synaptic Transmission, Sodium Currents, Neurotransmission +18

2-Amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission—II Biochemical properties

Jesús Bénavidès · Neuropharmacology · 1985 · 206 citations

Biochemistry, Neurophysiology, Possible Antagonist +12