Genotype–activity relationship for Mn-superoxide dismutase, glutathione peroxidase 1 and catalase in humans

Abstract

Interindividual variability of antioxidant enzyme activity in healthy young adults was partially explained by significant associations with three known genetic polymorphisms, and was further modified by gender and ethnicity. A substantial component of this variability may be attributable to differences in diet, environmental exposures, and additional genetic factors.