Regioselective synthesis of 6-aryl-benzo[h][1,2,4]-triazolo[5,1-b]quinazoline-7,8-diones as potent antitumoral agents

Sulfamic acid: a novel and efficient catalyst for the synthesis of aryl-14H-dibenzo[a.j]xanthenes under conventional heating and microwave irradiation

B. Rajitha, B. Sunil Kumar, Y. Thirupathi Reddy et al. · Tetrahedron Letters · 2005 · 220 citations

Natural Sciences, Chemical Engineering, Chemistry +16

beta-Lapachone, a novel DNA topoisomerase I inhibitor with a mode of action different from camptothecin.

C J Li, Lidia Averboukh, Arthur B. Pardee · Journal of Biological Chemistry · 1993 · 218 citations · Full text

Medicine, Biochemistry, Pharmacology +14

Potent antitumor activity of synthetic 1,2-Naphthoquinones and 1,4-Naphthoquinones

Ngampong Kongkathip, Boonsong Kongkathip, Pongpun Siripong et al. · Bioorganic & Medicinal Chemistry · 2003 · 216 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11

Beta-lapachone-mediated apoptosis in human promyelocytic leukemia (HL-60) and human prostate cancer cells: a p53-independent response.

Sarah M. Planchon, Shelly M. Wuerzberger, Benjamín Frydman et al. · PubMed · 1995 · 205 citations · Full text

Medicine, Oncology, Pharmacology +17

Anti-inflammatory effects of β-lapachone in lipopolysaccharide-stimulated BV2 microglia

Dong‐Oh Moon, Yung Hyun Choi, Nam-Duk Kim et al. · International Immunopharmacology · 2007 · 180 citations

Medicine, Immunology, Pharmacology +13