Concepedia

Publication | Open Access

CD4+CD25+FOXP3+ Regulatory T Cells Suppress Anti-Tumor Immune Responses in Patients with Colorectal Cancer

DOIFull Paper Access

216

Citations

30

References

2006

Year

Sarah L. Clarke, Gareth Betts, Andrea Plant, Kate Wright, Tariq El‐Shanawany, Richard Harrop, Jared Torkington, B I Rees, Geraint T. Williams, Awen Gallimore,
PLoS ONE

Abstract

Collectively, these data demonstrate that Treg capable of inhibiting tumor associated antigen-specific immune responses are enriched in patients with CRC. These results support a rationale for manipulating Treg to enhance cancer immunotherapy.

References

YearCitations

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