Pharmacological characterization of YM598, an orally active and highly potent selective endothelin ETA receptor antagonist

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

Natural Sciences, Biochemistry, Chemistry +17

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

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Life Sciences, Cell Biology, Physiology +9

SOME QUANTITATIVE USES OF DRUG ANTAGONISTS

O. ARUNLAKSHANA, H. O. Schild · British Journal of Pharmacology and Chemotherapy · 1959 · 4K citations · Full text

Medicine, Pharmacology, General Pharmacology +16

Cloning and expression of a cDNA encoding an endothelin receptor

Hiroshi Arai, Seiji Hori, Ichiro Aramori et al. · Nature · 1990 · 2.6K citations

Life Sciences, Cell Biology, Physiology +7