Asymmetric total synthesis of natural pyrrolizidine alkaloid, (+)-alexine

Australine, a Novel Pyrrolizidine Alkaloid Glucosidase Inhibitor from Castanospermum australe

Russell J. Molyneux, Mabry Benson, Rosalind Y. Wong et al. · Journal of Natural Products · 1988 · 178 citations

Medicine, Medicinal Chemistry, Pharmacology +7

Isolation from and x-ray crystal structure of alexine, (1r,2r,3r,7s,8s)-3-hydroxymethyl-1,2,7-trihydroxypyrrolizidine [(2r,3r,4r,5s,6s)-2-hydroxymethyl-1-azabicyclo[3.3.0]octan-3,4,6-triol], a unique pyrrolizidine alkaloid

Robert J. Nash, Linda E. Fellows, Janet V. Dring et al. · Tetrahedron Letters · 1988 · 126 citations

Natural Sciences, Chemistry, Medicinal Chemistry +12

Casuarine: A very highly oxygenated pyrrolizidine alkaloid

Robert J. Nash, Paul I. Thomas, Roger D. Waigh et al. · Tetrahedron Letters · 1994 · 102 citations

Pharmacy, Chemistry, Medicinal Chemistry +5

Total synthesis of natural (−)-codonopsinine employing stereoselective reduction of quaternary α-hydroxypyrrolidine

Hidemi Yoda, Tomohito Nakajima, Kunihiko Takabe · Tetrahedron Letters · 1996 · 64 citations

Natural Sciences, Chemistry, Organic Chemistry +6

7-Deoxy-6-epi-castanospermine, a Trihydroxyindolizidine Alkaloid Glycosidase Inhibitor from Castanospermum australe

Russell J. Molyneux, Joseph E. Tropea, Alan D. Elbein · Journal of Natural Products · 1990 · 61 citations

Medicine, Medicinal Chemistry, Pharmacology +12