Concepedia

Effects of sustained hyperoxia on revascularization in experimental retinopathy of prematurity.

Xiaolin Gu, Sara Samuel, Mohamed El-Shabrawey, Ruth B. Caldwell, Manuela Bartoli, Dennis M. Marcus, Steven E. Brooks

PubMed · 2002 · 79 citations · 27 references

Abstract

The antiangiogenic effect of hyperoxia on retinal capillaries is strongly dependent on postnatal age. A protocol of continuous 75% supplemental oxygen accelerates recovery of inner retinal vasculature and prevents vitreous neovascularization, by a mechanism that may involve preservation of inner retinal glia.

References

27

Oxygen-induced retinopathy in the mouse.

Lois Elaine Hodgson Smith, Eva Wesolowski, Angela McLellan et al. · PubMed · 1994 · 1.6K citations

Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity

Itzhak Hemo, Ahuva Itin, Jacob Pe’er et al. · Nature Medicine · 1995 · 1.6K citations

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Pigment Epithelium-Derived Factor: A Potent Inhibitor of Angiogenesis

David W. Dawson, Olga V. Volpert, Paul Gillis et al. · Science · 1999 · 1.5K citations

A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF

Laura E. Benjamin, Itzhak Hemo, Eli Keshet · Development · 1998 · 1.2K citations

Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia

Jennifer D. Stone, Ahuva Itin, Tamir Alon et al. · Journal of Neuroscience · 1995 · 1K citations · Full text

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