Fusidienol: A novel inhibitor of Ras farnesyl-protein transferase from Fusidium griseum

Inhibition of purified p21 farnesyl:protein transferase by Cys-AAX tetrapeptides

Yuval Reiss, Joseph L. Goldstein, Miguel C. Seabra et al. · Cell · 1990 · 815 citations

Life Sciences, Biochemistry, Molecular Biology +9

Benzodiazepine Peptidomimetics: Potent Inhibitors of Ras Farnesylation In Animal Cells

Guy L. James, Joseph L. Goldstein, Michael S. Brown et al. · Science · 1993 · 629 citations

Medicine, Oncology, Pharmacology +15

Selective Inhibition of <i>ras</i> -Dependent Transformation by a Farnesyltransferase Inhibitor

Nancy E. Kohl, Scott D. Mosser, S. J. DESOLMS et al. · Science · 1993 · 582 citations

Medicine, Oncology, Pharmacology +13

Identification of Ras farnesyltransferase inhibitors by microbial screening.

Masatake Hara, Koji Akasaka, Shiro Akinaga et al. · Proceedings of the National Academy of Sciences · 1993 · 260 citations

Life Sciences, Biochemistry, Microbiology +9

Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo.

D. L. Pompliano, S.D. Mosser, Elaine Rands et al. · Journal of Biological Chemistry · 1993 · 258 citations · Full text

Medicine, Cancer Biology, Oncology +12