Time resolved absorption study of the reaction of hydroxyurea with sickle cell hemoglobin

Singular value decomposition and least squares solutions

Gene H. Golub, C. Reinsch · Numerische Mathematik · 1970 · 2.9K citations

Natural Sciences, Mathematics, Differential Equations +10

Effect of Hydroxyurea on the Frequency of Painful Crises in Sickle Cell Anemia

Samuel Charache, Michael L. Terrin, Richard D. Moore et al. · New England Journal of Medicine · 1995 · 2.3K citations · Full text

Medicine, Hematology, Pharmacology +9

A Specific Chemical Difference Between the Globins of Normal Human and Sickle-Cell Anæmia Hæmoglobin

Vernon M. Ingram · Nature · 1956 · 884 citations

Medicine, Biochemistry, Hematology +10

Kinetics and Mechanism of Deoxyhemoglobin S Gelation: A New Approach to Understanding Sickle Cell Disease

James Hofrichter, Philip D. Ross, William A. Eaton · Proceedings of the National Academy of Sciences · 1974 · 509 citations · Full text

Natural Sciences, Biophysics, Physiology +15

Kinetics of sickle hemoglobin polymerization

Frank A. Ferrone, James Hofrichter, William A. Eaton · Journal of Molecular Biology · 1985 · 505 citations

Natural Sciences, Biochemistry, Hematology +11