Activation of Caspases Measured in Situ by Binding of Fluorochrome-Labeled Inhibitors of Caspases (FLICA): Correlation with DNA Fragmentation

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

Yuri Lazebnik, Scott H. Kaufmann, Serge Desnoyers et al. · Nature · 1994 · 2.6K citations

Life Sciences, Biochemistry, Molecular Biology +10

Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis.

Scott H. Kaufmann, Serge Desnoyers, Yvonne Ottaviano et al. · PubMed · 1993 · 1.9K citations

Life Sciences, Biochemistry, Molecular Biology +14

Caspases: their intracellular localization and translocation during apoptosis

Boris Zhivotovsky, Afshin Samali, Annie Gahm et al. · Cell Death and Differentiation · 1999 · 354 citations

Life Sciences, Cell Biology, Molecular Biology +12

Induction of DNA strand breaks associated with apoptosis during treatment of leukemias.

Wojciech Gorczyca, K Bigman, Abraham Mittelman et al. · PubMed · 1993 · 291 citations

Life Sciences, Molecular Biology, Oncology +10

DNA STRAND BREAKS OCCURRING DURING APOPTOSIS - THEIR EARLY INSITU DETECTION BY THE TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE AND NICK TRANSLATION ASSAYS AND PREVENTION BY SERINE PROTEASE INHIBITORS

Wojciech Gorczyca, Silvia Bruno, RJ DARZYNKIEWICZ et al. · International Journal of Oncology · 1992 · 251 citations

Life Sciences, Molecular Biology, Pharmacology +17