The anti-inflammatory activities of an extract and compounds isolated from Platycladus orientalis (Linnaeus) Franco in vitro and ex vivo

Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation

Bengt Samuelsson · Science · 1983 · 2.8K citations

Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A4 synthase activities.

Carol A. Rouzer, Takashi Matsumoto, B Samuelsson · Proceedings of the National Academy of Sciences · 1986 · 309 citations · Full text

Lipid Peroxidation, Immunology, Redox Biology +18

Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acid.

Takao Shimizu, Olof Rådmark, B Samuelsson · Proceedings of the National Academy of Sciences · 1984 · 290 citations · Full text

Biosynthesis, Biochemistry, Medicine +14

Contribution of Nitric Oxide Synthases 1, 2, and 3 to Airway Hyperresponsiveness and Inflammation in a Murine Model of Asthma

George T. De Sanctis, James A. MacLean, Kaoru Hamada et al. · The Journal of Experimental Medicine · 1999 · 211 citations · Full text

Inflammation, Asthma, Inflammatory Lung Disease +14

Inhibitors of 5-lipoxygenase: a therapeutic potential yet to be fully realized?

Robert N. Young · European Journal of Medicinal Chemistry · 1999 · 133 citations

Medicinal Chemistry, Therapeutic Potential, Bioorganic Chemistry +11