What are the functional deficits produced by hippocampal and perirhinal cortex lesions?

A.R. Mayes, Rob van Eijk, Patricia Gooding, Clémence Isaac, J.S. Holdstock

Behavioral and Brain Sciences · 1999 · 19 citations · 0 references

Concepts

Abstract

A hippocampal patient is described who shows preserved item recognition and simple recognition-based recollection but impaired recall and associative recognition. These data and other evidence suggest that contrary to Aggleton & Brown's target article, Papez circuit damage impairs only complex item-item-context recollection. A patient with perirhinal cortex damage and a delayed global memory deficit, apparently inconsistent with A&B's framework, is also described.