Concepedia

Platelet activation as a potential mechanism of GP IIb/IIIa inhibitor-induced thrombocytopenia

Karlheinz Peter, Andreas Straub, Benedikt Köhler, Martin Volkmann, Meike Schwarz, W. Kübler, Christoph Bode

The American Journal of Cardiology · 1999 · 69 citations · 12 references

DOI

Concepts

References

12

Synergistic Roles for Receptor Occupancy and Aggregation in Integrin Transmembrane Function

Shingo Miyamoto, Steven K. Akiyama, Kenneth M. Yamada · Science · 1995 · 894 citations

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Flow cytometry: a clinical test of platelet function

AD Michelson · Blood · 1996 · 492 citations · Full text

, , +16

Ligands “activate” integrin αIIbβ3 (platelet GPIIb-IIIa)

Xiaoping Du, Edward F. Plow, Andrew L. Frelinger et al. · Cell · 1991 · 490 citations

, , +12

Monoclonal antibodies to ligand-occupied conformers of integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) alter receptor affinity, specificity, and function.

Andrew L. Frelinger, Xiaoping Du, Edward F. Plow et al. · Journal of Biological Chemistry · 1991 · 359 citations · Full text

, , +17

Pharmacodynamic Profile of Short-term Abciximab Treatment Demonstrates Prolonged Platelet Inhibition With Gradual Recovery From GP IIb/IIIa Receptor Blockade

Mary Ann Mascelli, Ellen T. Lance, Lakshmi Damaraju et al. · Circulation · 1998 · 288 citations

, , +17