Publication | Open Access
The role of lipophilicity in transmembrane anion transport
96
Citations
25
References
2012
Year
Proteinlipid InteractionMedicinal ChemistryTransmembrane Anion TransportDrug TargetBiochemistryNatural SciencesMembrane TransportMedicineReceptor (Biochemistry)Mechanism Of ActionSynthetic MoleculesTambjamine AlkaloidsLipid MovementCellular BiochemistryChemical BiologyPharmacologyCellular PhysiologyDrug Discovery
The transmembrane anion transport activity of a series of synthetic molecules inspired by the structure of tambjamine alkaloids can be tuned by varying the lipophilicity of the receptor, with carriers within a certain log P range performing best.
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