Urinary malondialdehyde and 8-hydroxydeoxyguanosine as potential markers of oxidative stress in industrial art glass workers

Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

Shinya Shibutani, Masaru Takeshita, Arthur P. Grollman · Nature · 1991 · 2.2K citations

Life Sciences, Biochemistry, Molecular Biology +13

Free radicals, antioxidants, and human disease: where are we now?

Barry Halliwell, John M.C. Gutteridge, C E Cross · PubMed · 1992 · 2.2K citations

Life Sciences, Biochemistry, Toxicology +14

8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions.

Keith C. Cheng, D S Cahill, Hiroshi Kasai et al. · Journal of Biological Chemistry · 1992 · 1.8K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine.

César G. Fraga, Mark K. Shigenaga, J W Park et al. · Proceedings of the National Academy of Sciences · 1990 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +16

Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair

Hiroshi Kasai, P. F. Crain, Yoshiyuki Kuchino et al. · Carcinogenesis · 1986 · 923 citations

Medicine, Genetics, Molecular Biology +17