Concepedia

Comparison of the potency, kinetics and voltage-dependency of a series of uncompetitive NMDA receptor antagonists in vitro with anticonvulsive and motor impairment activity in vivo

Chris G. Parsons, G. Quack, I. Bresink, L Baran, Edmund Przegaliński, Wojciech Kostowski, Paweł Krząścik, Sabine Hartmann, Wojciech Danysz

Neuropharmacology · 1995 · 312 citations · 51 references

DOI

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References

51

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

, , +14

A SIMPLIFIED METHOD OF EVALUATING DOSE-EFFECT EXPERIMENTS

J.T. LITCHFIELD, Frank Wilcoxon · Journal of Pharmacology and Experimental Therapeutics · 1949 · 7.3K citations

, , +12

Magnesium gates glutamate-activated channels in mouse central neurones

Linda M. Nowak, Pìotr Bregestovski, Philippe Ascher et al. · Nature · 1984 · 4K citations

, , +14

Glycine potentiates the NMDA response in cultured mouse brain neurons

John Johnson, Philippe Ascher · Nature · 1987 · 3.1K citations

, , +14

Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones

Mark L. Mayer, Gary L. Westbrook, Peter B. Guthrie · Nature · 1984 · 2.9K citations

, , +16