Concepedia

Publication | Open Access

IL-17 Induces an Expanded Range of Downstream Genes in Reconstituted Human Epidermis Model

DOIFull Paper Access

176

Citations

51

References

2014

Year

Andrea Chiricozzi, Kristine Nograles, Leanne M. Johnson-Huang, Judilyn Fuentes‐Duculan, Irma Cardinale, Kathleen M. Bonifacio, Nicholas Gulati, Hiroshi Mitsui, Emma Guttman‐Yassky, Mayte Suárez‐Fariñas,
PLoS ONE

Abstract

The genes identified in IL-17-treated RHE are likely relevant to the IL-17 effects in psoriasis, since ixekizumab (anti-IL-17A agent) strongly suppressed the "RHE" genes in psoriasis patients treated in vivo with this IL-17 antagonist.

References

YearCitations

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