Varicella Zoster Virus Ischemic Optic Neuropathy and Subclinical Temporal Artery Involvement

Abstract

Although in previously studied patients who died of chronic VZV vasculopathy after 10 to 12 months, VZV antigen was present exclusively in the intima, collective analyses of chronic cases and the asymptomatic VZV-infected temporal artery suggest that virus enters arteries through the adventitia and spreads transmurally to the intima.