COX-2 expression correlates with VEGF-C and lymph node metastases in patients with head and neck squamous cell carcinoma

A novel vascular endothelial growth factor, VEGF‐C, is a ligand for the Flt4 (VEGFR‐3) and KDR (VEGFR‐2) receptor tyrosine kinases.

Vladimir Joukov, Katri Pajusola, Arja Kaipainen et al. · The EMBO Journal · 1996 · 1.7K citations · Full text

Life Sciences, Cell Biology, Pharmacology +11

Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential

Masahiko Tsujii, Sunao Kawano, Raymond N. DuBois · Proceedings of the National Academy of Sciences · 1997 · 1.4K citations

Medicine, Oncology, Pharmacology +13

Prevention of Second Primary Tumors with Isotretinoin in Squamous-Cell Carcinoma of the Head and Neck

Waun Ki Hong, S. M. Lippman, Loretta M. Itri et al. · New England Journal of Medicine · 1990 · 1.4K citations · Full text

Medicine, Oncology, Neoplasia +12

Expression of cyclooxygenase-1 and -2 in human colorectal cancer.

Hajime Sano, Yutaka Kawahito, Ronald L. Wilder et al. · PubMed · 1995 · 1.1K citations

Medicine, Oncology, Pharmacology +10

Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas.

Toyoaki Hida, Yasushi Yatabe, Hiroyuki Achiwa et al. · PubMed · 1998 · 825 citations

Medicine, Oncology, Pathology +17