Concepedia

Left-Right Symmetry Breaking in Tissue Morphogenesis via Cytoskeletal Mechanics

Ting‐Hsuan Chen, Jeffrey J. Hsu, Xin Zhao, Chunyan Guo, Margaret N. Wong, Yi Huang, Zongwei Li, Alan Garfinkel, Chih‐Ming Ho, Yin Tintut,

Circulation Research · 2012 · 125 citations · 32 references

DOIFull text

Open access

Abstract

Our results show that adult stem cells retain inherent LR asymmetry that elicits de novo macroscale tissue morphogenesis, indicating that mechanical induction is required for cellular LR specification.

References

32

Matrix Elasticity Directs Stem Cell Lineage Specification

Adam J. Engler, Shamik Sen, H. Lee Sweeney et al. · Cell · 2006 · 13.5K citations · Full text

, , +7

The chemical basis of morphogenesis

Alan Turing · Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 1952 · 11.5K citations

Geometric cues for directing the differentiation of mesenchymal stem cells

K. Kilian, Branimir Bugarija, Bruce T. Lahn et al. · Proceedings of the National Academy of Sciences · 2010 · 1.8K citations · Full text

Fiber Orientation in the Canine Left Ventricle during Diastole and Systole

Daniel D. Streeter, Henry M. Spotnitz, DALI P. PATEL et al. · Circulation Research · 1969 · 1.4K citations

, , +21

Bone morphogenetic protein expression in human atherosclerotic lesions.

Kristina I. Boström, Karol E. Watson, Stephen E. Van Horn et al. · Journal of Clinical Investigation · 1993 · 1K citations · Full text