Studies toward the synthesis of natural and unnatural dienediynes 1. Approaches to a functionalised bicyclic ring system

The structure of neocarzinostatin chromophore possessing a novel bicyclo-[7,3,0]dodecadiyne system

Kiyoto Edo, Michinao Mizugaki, Yoshio Koide et al. · Tetrahedron Letters · 1985 · 325 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Mechanism of neocarzinostatin action: role of DNA microstructure in determination of chemistry of bistranded oxidative damage

I. Goldberg · Accounts of Chemical Research · 1991 · 320 citations

Medicine, Chemistry, Pharmacology +9

Reaction of C60 with diacyl peroxides containing perfluoroalkyl groups. The first example of electron transfer reaction via C60+· in solution

Masato Yoshida, Yoshihiro Morinaga, Masahiko Iyoda et al. · Tetrahedron Letters · 1993 · 136 citations

Natural Sciences, Chemistry, Organic Chemistry +8

Studies on tumor promoters. 7. The synthesis of a potentially general precursor of the tiglianes, daphnanes, and ingenanes

Paul A. Wender, Hee Yoon Lee, Robert S. Wilhelm et al. · Journal of the American Chemical Society · 1989 · 129 citations

Medicine, Oncology, Cancer Pharmacology +5

General methodology for the synthesis of neocarzinostatin chromophore analogs: intramolecular chromium-mediated closures for strained ring synthesis

Paul A. Wender, Jeffrey A. McKinney, Chisato Mukai · Journal of the American Chemical Society · 1990 · 120 citations

Pharmacy, Chemistry, Medicinal Chemistry +7