Human prolactin and its antagonist, hPRL-G129R, regulate bax and bcl-2 gene expression in human breast cancer cells and transgenic mice

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax

Xiao-Ming Yin, Zoltán N. Oltvai, Stanley J. Korsmeyer · Nature · 1994 · 1.3K citations

Signal Transduction, Bh2 Domains, Apoptosis +6

Transgenic Mice Overexpressing the Prolactin Gene Develop Dramatic Enlargement of the Prostate Gland¹

Håkan Wennbo, Jon Kindblom, Olle Isaksson et al. · Endocrinology · 1997 · 187 citations · Full text

BAR: An apoptosis regulator at the intersection of caspases and Bcl-2 family proteins

Hong Zhang, Qunli Xu, Stanisław Krajewski et al. · Proceedings of the National Academy of Sciences · 2000 · 185 citations

PRL Activates the Cyclin D1 Promoter Via the Jak2/Stat Pathway

Jennifer L. Brockman, Matthew D. Schroeder, Linda A. Schuler · Molecular Endocrinology · 2002 · 159 citations

Quantification of prolactin receptor mRNA in multiple human tissues and cancer cell lines by real time RT-PCR

SK Peirce, W Y Chen · Journal of Endocrinology · 2001 · 92 citations · Full text

Breast Oncology, Pathology, Molecular Biology +18