Mice overexpressing the gene for heparin-binding epidermal growth factor-like growth factor (HB-EGF) have increased resistance to hemorrhagic shock and resuscitation

Intestinal Mucosal Lesion in Low-Flow States

Chu-Jeng Chiu · Archives of Surgery · 1970 · 1.8K citations

Life Sciences, Pathology, Physiology +17

A Heparin-Binding Growth Factor Secreted by Macrophage-Like Cells That Is Related to EGF

Shigeki Higashiyama, Judith A. Abraham, John C. Fiddes et al. · Science · 1991 · 1.1K citations

Life Sciences, Cancer Biology, Cell Biology +14

cis Elements of the Villin Gene Control Expression in Restricted Domains of the Vertical (Crypt) and Horizontal (Duodenum, Cecum) Axes of the Intestine

Blair Madison, Laura Dunbar, Xiaotan T. Qiao et al. · Journal of Biological Chemistry · 2002 · 760 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Heparin-binding EGF-like growth factor stimulation of smooth muscle cell migration: dependence on interactions with cell surface heparan sulfate

Shigeki Higashiyama, JA Abraham, Michael Klagsbrun · The Journal of Cell Biology · 1993 · 364 citations · Full text

Life Sciences, Biochemistry, Cell Biology +12

Diphtheria Toxin Binds to the Epidermal Growth Factor (EGF)-like Domain of Human Heparin-binding EGF-like Growth Factor/Diphtheria Toxin Receptor and Inhibits Specifically Its Mitogenic Activity

T. Mitamura, Shigeki Higashiyama, Naoyuki Taniguchi et al. · Journal of Biological Chemistry · 1995 · 305 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +13