Identification of CTL epitopes in hepatitis C virus by a genome-wide computational scanning and a rational design of peptide vaccine

Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions.

M Nei, T Gojobori · Molecular Biology and Evolution · 1986 · 5K citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Viral Persistence Alters CD8 T-Cell Immunodominance and Tissue Distribution and Results in Distinct Stages of Functional Impairment

E. John Wherry, Joseph N. Blattman, Kaja Murali‐Krishna et al. · Journal of Virology · 2003 · 1.6K citations

Life Sciences, Immunology, Infectious Diseases +17

HIV-Specific Cd8+ T Cells Produce Antiviral Cytokines but Are Impaired in Cytolytic Function

Victor Appay, Douglas F. Nixon, Sean M. Donahoe et al. · The Journal of Experimental Medicine · 2000 · 864 citations · Full text

Life Sciences, Cell Biology, Immunology +17

HCV Persistence and Immune Evasion in the Absence of Memory T Cell Help

Arash Grakoui, Naglaa H. Shoukry, David J. Woollard et al. · Science · 2003 · 820 citations

Life Sciences, Immunology, Infectious Diseases +17

Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease

Robert Thimme, Jens Bukh, Hans Christian Spangenberg et al. · Proceedings of the National Academy of Sciences · 2002 · 634 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17