Concepedia

Unexpected Synthesis of 2,4,5-Trisubstituted Oxazoles via a Tandem Aza-Wittig/Michael/Isomerization Reaction of Vinyliminophosphorane

Hai Xie, Ding Yuan, Ming‐Wu Ding

The Journal of Organic Chemistry · 2012 · 43 citations · 34 references

DOI

Concepts

Abstract

2,4,5-Trisubstituted oxazoles 6 were unexpectedly prepared from a tandem reaction of vinyliminophosphorane 3 with various acyl chlorides in a one-pot fashion.

References

34

The aza-Wittig reaction: an efficient tool for the construction of carbon–nitrogen double bonds

Francisco Palácios, Concepción Alonso, Domitila Aparicio et al. · Tetrahedron · 2006 · 386 citations

, , +15

An Efficient [2 + 2 + 1] Synthesis of 2,5-Disubstituted Oxazoles via Gold-Catalyzed Intermolecular Alkyne Oxidation

Wei‐Min He, Chaoqun Li, Liming Zhang · Journal of the American Chemical Society · 2011 · 369 citations

, , +16

Neopeltolide, a Macrolide from a Lithistid Sponge of the Family Neopeltidae

Amy E. Wright, Julianne Cook Botelho, Esther A. Guzmán et al. · Journal of Natural Products · 2007 · 195 citations

, , +17

TBHP/I<sub>2</sub>-Mediated Domino Oxidative Cyclization for One-Pot Synthesis of Polysubstituted Oxazoles

Huanfeng Jiang, Huawen Huang, Hua Cao et al. · Organic Letters · 2010 · 185 citations

, , +12

Facile Synthesis of Polysubstituted Oxazoles via A Copper-Catalyzed Tandem Oxidative Cyclization

Changfeng Wan, Jintang Zhang, Sujing Wang et al. · Organic Letters · 2010 · 168 citations

, , +9