Organic Letters · 2005 · 59 citations · 7 references
Life SciencesBiochemistryChemistryCarbohydrate BiochemistryCarbohydrate ChemistryMolecular RecognitionAnion RecognitionCarbohydrate RecognitionCarbohydrate StructureGlycan RecognitionAqueous SolvationCarbohydrate ReceptorsIon Pair FormationMacromolecular Complex FormationPair FormationSugar Recognition
A tris-cationic artificial receptor 1 efficiently binds anionic carbohydrates even in aqueous solution as shown by NMR and UV titration experiments. Complex formation involves both ion pair formation and H-bonds to the sugar, explaining the preference for saccharides compared to simple anions and the observed selectivities among different sugars. [structure: see text]
7