Synthesis of Polysubstituted Aromatic Acids Using an Intramolecular Benzyne Cyclisation

David R. Reavill, Stewart K. Richardson

Synthetic Communications · 1990 · 13 citations · 6 references

Concepts

Abstract

Abstract The protected haloanilines 3 and 4 undergo base catalysed elimination of halide to give aryne intermediates. These serve as useful precursors for the synthesis of the aromatic acids 7 and 8.

References

6