Concepedia

Simple and Efficient <i>Friedel–Crafts</i> Alkylation of 1<i>H</i>‐Indole with Electron‐Deficient Alkenes Promoted by Zinc Acetate

H. M. Meshram, D. Aravind Kumar, B. Chennakesava Reddy

Helvetica Chimica Acta · 2009 · 26 citations · 13 references

DOI

Concepts

Abstract

Abstract magnified image An efficient method for the Friedel–Crafts alkylation of 1 H ‐indole with nitro alkenes in the presence of zinc acetate is described. The procedure is applicable to a variety of nitro alkenes and substituted indoles, and the yields are very high.

References

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