Synthesis and Antifungal Activity of 5,6-Dihydro-3- methyl-1,4-dioxin-2-carboxamides

Abstract

Seven N -aryl-5,6-dihydro-3-methyl-1,4-dioxin-2-carboxamides were prepared as potential fungicides. The fungicidal activity of the dioxincarboxamides was evaluated against bean rust, a major disease of cereal crops. Structure−activity relationships for the screened compounds are discussed. The fungicidal activity of the dioxincarboxamides is correlated with that of the structurally similar commercial fungicide, carboxin. Keywords: Dioxincarboxamides; fungicides; bean rust