Concepedia

Experimental Characterization and Computational Study of Unique C,N-Chelated Lithium Dianions

Jocelyn M. Gruver, Scott P. West, David B. Collum, Richmond Sarpong

Journal of the American Chemical Society · 2010 · 33 citations · 12 references

DOI

Abstract

The structure of a unique C,N-chelated dilithio dianion has been established as a solvated monomeric species using a combination of NMR and computational techniques. The highly ordered structure of the dianion may be important in its reactivity in an oxidative C-N bond-forming process.

References

12

Structures of Classical Reagents in Chemical Synthesis: (<i>n</i>BuLi)<sub>6</sub>, (<i>t</i>BuLi)<sub>4</sub>, and the Metastable (<i>t</i>BuLi · Et<sub>2</sub>O)<sub>2</sub>

Thomas Kottke, Dietmar Stalke · Angewandte Chemie International Edition in English · 1993 · 239 citations · Full text

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Unified Strategy for the Synthesis of the “Miscellaneous” <i>Lycopodium</i> Alkaloids: Total Synthesis of (±)-Lyconadin A

Alakesh Bisai, Scott P. West, Richmond Sarpong · Journal of the American Chemical Society · 2008 · 110 citations

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Total Synthesis of (+)-Lyconadin A and Related Compounds via Oxidative C−N Bond Formation

Scott P. West, Alakesh Bisai, Andrew D. Lim et al. · Journal of the American Chemical Society · 2009 · 98 citations

Indolyl esters and amides related to indomethacin are selective COX-2 inhibitors

Amit S. Kalgutkar, Brenda C. Crews, Sam Saleh et al. · Bioorganic & Medicinal Chemistry · 2005 · 83 citations

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Synthesis of (−)-Epibatidine

David A. Evans, Karl A. Scheidt, C. Wade Downey · Organic Letters · 2001 · 72 citations