The neurosteroid pregnenolone sulfate blocks deficits induced by a competitive NMDA antagonist in active avoidance and lever-press learning tasks in mice

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

Richard Morris, Eric Anderson, Gary Lynch et al. · Nature · 1986 · 3.6K citations

Functional Selectivity, Medicine, Selective Impairment +7

Steroid Hormone Metabolites Are Barbiturate-Like Modulators of the GABA Receptor

Maria Dorota Majewska, Neil L. Harrison, Rochelle D. Schwartz et al. · Science · 1986 · 2.2K citations

Neuroactive steroids

Steven M. Paul, Robert H. Purdy · The FASEB Journal · 1992 · 1.3K citations · Full text

Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain.

R. H. Purdy, A. Leslie Morrow, Perry H. Moore et al. · Proceedings of the National Academy of Sciences · 1991 · 958 citations · Full text

Pharmacotherapy, Glucocorticoid, Social Sciences +21

Steroid Binding at σ Receptors Suggests a Link Between Endocrine, Nervous, and Immune Systems

Tsung‐Ping Su, Edythe D. London, Jerome H. Jaffe · Science · 1988 · 541 citations

Immune Systems, Immune Regulation, Immunology +17