Favorable prognostic impact of NPM1 gene mutations in childhood acute myeloid leukemia, with emphasis on cytogenetically normal AML

Cytoplasmic Nucleophosmin in Acute Myelogenous Leukemia with a Normal Karyotype

Brunangelo Falini, Cristina Mecucci, Enrico Tiacci et al. · New England Journal of Medicine · 2005 · 1.9K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +14

Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis

Christian Thiede, Christine Steudel, Brigitte Mohr et al. · Blood · 2002 · 1.7K citations · Full text

Medicine, Genetics, Hematology +14

Major nucleolar proteins shuttle between nucleus and cytoplasm

R.A. Borer, Christian F. Lehner, Hans M. Eppenberger et al. · Cell · 1989 · 1.1K citations

Life Sciences, Cell Biology, Molecular Biology +12

Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: interaction with other gene mutations

Konstanze Döhner, Richard F. Schlenk, Marianne Habdank et al. · Blood · 2005 · 845 citations · Full text

Life Sciences, Genetics, Oncology +11

The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia

Rosemary E. Gale, Claire Green, Christopher Allen et al. · Blood · 2007 · 744 citations

Medicine, Genetics, Molecular Genetics +15