The Journal of Antibiotics · 1971 · 51 citations · 7 references
PharmacyMedicinal ChemistryPharmacologyDrug DesignPharmacodynamicsStructure-activity RelationshipsEnzyme InhibitionPeptide Drug DiscoveryPeptide ProdrugsSubstituent Effects
Leupeptins produced by various species of Actinomycetes, strongly inhibit proteases such as plasmin, trypsin and papainlj2'3). We previously reported4) the structures of two major components, acetyl-L-leucyl-L-
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Structure and synthesis of nojirimycin
S Inouye, T. Tsuruoka, Takeo Itô et al. · Tetrahedron · 1968 · 369 citations
LEUPEPTINS, NEW PROTEASE INHIBITORS FROM ACTINOMYCETES
TAKAAKI AOYAGI, TOMIO TAKEUCHI, A Matsuzaki et al. · The Journal of Antibiotics · 1969 · 258 citations · Full text
BIOLOGICAL ACTIVITIES OF LEUPEPTINS
TAKAAKI AOYAGI, Setsuko Miyata, MASAKO NANBO et al. · The Journal of Antibiotics · 1969 · 221 citations · Full text
The structure of nojirimycin, a piperidinose sugar antibiotic.
Shigeharu Inouye, Takashi Tsuruoka, T Nida · PubMed · 1966 · 120 citations