From DNA sequence to biological function

Whole-Genome Random Sequencing and Assembly of <i>Haemophilus influenzae</i> Rd

Robert Fleischmann, Mark D. Adams, Owen White et al. · Science · 1995 · 5.6K citations

Life Sciences, Genetics, Microbiology +14

[12] One-step gene disruption in yeast

Rodney Rothstein · Methods in enzymology on CD-ROM/Methods in enzymology · 1983 · 3.3K citations

Life Sciences, Genetics, Molecular Genetics +7

New heterologous modules for classical or PCR‐based gene disruptions in <i>Saccharomyces cerevisiae</i>

Achim Wach, Arndt Brachat, Rainer Pöhlmann et al. · Yeast · 1994 · 2.6K citations

Life Sciences, Genetics, Molecular Genetics +16

Complementary DNA Sequencing: Expressed Sequence Tags and Human Genome Project

Mark D. Adams, Jenny M. Kelley, Jeannine D. Gocayne et al. · Science · 1991 · 2.3K citations

Life Sciences, Genetics, Molecular Biology +12

The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest.

Cheng‐Ting Chien, Paul L. Bartel, Rolf Sternglanz et al. · Proceedings of the National Academy of Sciences · 1991 · 1.5K citations

Life Sciences, Genetics, Molecular Biology +13