Concepedia

Increased risk of antituberculosis drug‐induced hepatotoxicity in individuals with glutathione <i>S</i>‐transferase M1 ‘null’ mutation

Bidyut Roy, Abhijit Chowdhury, Somnath Kundu, Amal Santra, Badal Dey, Madan Chakraborty, Partha P. Majumder

Journal of Gastroenterology and Hepatology · 2001 · 186 citations · 27 references

DOI

Abstract

Homozygous 'null' mutation at the GSTM1 gene might predispose an individual to ATD-induced hepatotoxicity.

References

27

A simple salting out procedure for extracting DNA from human nucleated cells

S.A. Miller, Dale D. Dykes, Herbert F. Polesky · Nucleic Acids Research · 1988 · 20.4K citations · Full text

, , +11

ACETAMINOPHEN-INDUCED HEPATIC NECROSIS. IV. PROTECTIVE ROLE OF GLUTATHIONE

J.R. Mitchell, David J. Jollow, William Z. Potter et al. · Journal of Pharmacology and Experimental Therapeutics · 1973 · 1.7K citations

Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism

Sally Pemble, Karsten Schroeder, S R Spencer et al. · Biochemical Journal · 1994 · 1.3K citations · Full text

, , +18

Selective Modification of Glutathione Metabolism

Alton Meister · Science · 1983 · 1.3K citations

, , +14

Theta, a new class of glutathione transferases purified from rat and man

David J. Meyer, B Coles, Sally Pemble et al. · Biochemical Journal · 1991 · 737 citations · Full text