Pretreatment of Rho Kinase Inhibitor Inhibits Systemic Inflammation and Prevents Endotoxin-Induced Acute Lung Injury in Mice

Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins.

Rosario Perona, Silvia Montaner, Luisa Saniger et al. · Genes & Development · 1997 · 615 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Suppression of Inflammatory Cytokine Production by Carbon Monoxide Involves the JNK Pathway and AP-1

Danielle Morse, Zhihong Zhou, Roger J. Davis et al. · Journal of Biological Chemistry · 2003 · 377 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Multiple Signalling Pathways Lead to the Activation of the Nuclear Factor κB by the Rho Family of GTPases

Silvia Montaner, Rosario Perona, Luisa Saniger et al. · Journal of Biological Chemistry · 1998 · 230 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Inhibition of Rho-kinase protects the heart against ischemia/reperfusion injury

Weike Bao · Cardiovascular Research · 2004 · 222 citations

Medicine, Cardiology, Pharmacology +14

Rho kinase blockade prevents inflammation via nuclear factor κB inhibition: evidence in Crohn’s disease and experimental colitis

Jean‐Pierre Segain, Diane Raingeard de la Blétière, Vincent Sauzeau et al. · Gastroenterology · 2003 · 189 citations · Full text

Life Sciences, Immunology, Pathology +17