Cyclic GMP-dependent Protein Kinase Signaling Pathway Inhibits RhoA-induced Ca2+ Sensitization of Contraction in Vascular Smooth Muscle

Vincent Sauzeau, Hélène Le Jeune, Chrystelle Cario‐Toumaniantz, +6

Journal of Biological Chemistry

Human Urotensin II–Induced Contraction and Arterial Smooth Muscle Cell Proliferation Are Mediated by RhoA and Rho-Kinase

Vincent Sauzeau, Erik Le Mellionnec, Jacques Bertoglio, +3

Circulation Research

Muscle FunctionRhoa ActivationCytoskeletonCellular PhysiologyMuscle Physiology +15

Rho kinase blockade prevents inflammation via nuclear factor κB inhibition: evidence in Crohn’s disease and experimental colitis

Jean‐Pierre Segain, Diane Raingeard de la Blétière, Vincent Sauzeau, +6

Gastroenterology

InflammationChronic Inflammatory DiseasesAnti-inflammatoryMucosal ImmunologyImmunology +7

RhoA Expression Is Controlled by Nitric Oxide through cGMP-dependent Protein Kinase Activation

Vincent Sauzeau, Malvyne Rolli‐Derkinderen, Céline Marionneau, +2

Journal of Biological Chemistry

Mesenchymal Stem Cells Induce Suppressive Macrophages Through Phagocytosis in a Mouse Model of Asthma

Faouzi Braza, S. Dirou, Virginie Forest, +7

Stem Cells

AsthmaAcute Lung InjuryInflammatory Lung DiseaseLung InflammationImmunology +19

Rho-Associated Protein Kinase Contributes to Early Atherosclerotic Lesion Formation in Mice

Ziad Mallat, Andrea Gojová, Vincent Sauzeau, +7

Circulation Research

Vascular DiseaseImmunologyPathologyHyperlipidemiaOxidative Stress +21

Phosphorylation of Serine 188 Protects RhoA from Ubiquitin/Proteasome-Mediated Degradation in Vascular Smooth Muscle Cells

Malvyne Rolli‐Derkinderen, Vincent Sauzeau, Laurent Boyer, +5

Circulation Research

Inhibition of RhoA/Rho kinase pathway is involved in the beneficial effect of sildenafil on pulmonary hypertension

Christophe Guilluy, Vincent Sauzeau, Malvyne Rolli‐Derkinderen, +4

British Journal of Pharmacology

HypertensionPulmonary Arterial HypertensionPulmonary CirculationCardiovascular DiseaseRho Kinase +13

Vav3 proto-oncogene deficiency leads to sympathetic hyperactivity and cardiovascular dysfunction

Vincent Sauzeau, María A. Sevilla, Juan V. Rivas‐Elena, +4

Nature Medicine

Sympathetic HyperactivityNeurovirologyDisease PathophysiologyPhysiologyPathology +3

A mouse model for Costello syndrome reveals an Ang II–mediated hypertensive condition

Alberto J. Schuhmacher, Carmen Guerra, Vincent Sauzeau, +3

Journal of Clinical Investigation