Retrograde transport of the transmembrane estrogen receptor, G-protein-coupled-receptor-30 (GPR30/GPER) from the plasma membrane towards the nucleus

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Life Sciences, Biochemistry, Cell Biology +10

EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

Norbert Prenzel, Esther Zwick, Henrik Daub et al. · Nature · 1999 · 1.5K citations

Life Sciences, Biochemistry, Molecular Biology +15

Identity of an Estrogen Membrane Receptor Coupled to a G Protein in Human Breast Cancer Cells

Peter Thomas, Yefei Pang, Edward J. Filardo et al. · Endocrinology · 2004 · 1.4K citations · Full text

Life Sciences, Endocrinology, Molecular Biology +17

Estrogen-Induced Activation of Erk-1 and Erk-2 Requires the G Protein-Coupled Receptor Homolog, GPR30, and Occurs via Trans-Activation of the Epidermal Growth Factor Receptor through Release of HB-EGF

Edward J. Filardo, Jeffrey A. Quinn, Kirby I. Bland et al. · Molecular Endocrinology · 2000 · 1.3K citations · Full text

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Estrogen Action Via the G Protein-Coupled Receptor, GPR30: Stimulation of Adenylyl Cyclase and cAMP-Mediated Attenuation of the Epidermal Growth Factor Receptor-to-MAPK Signaling Axis

Edward J. Filardo, Jeffrey A. Quinn, A. Raymond Frackelton et al. · Molecular Endocrinology · 2002 · 854 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17