A. Raymond Frackelton

Estrogen-Induced Activation of Erk-1 and Erk-2 Requires the G Protein-Coupled Receptor Homolog, GPR30, and Occurs via Trans-Activation of the Epidermal Growth Factor Receptor through Release of HB-EGF

Edward J. Filardo, Jeffrey A. Quinn, Kirby I. Bland et al. · Molecular Endocrinology · 2000 · 1.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Estrogen Action Via the G Protein-Coupled Receptor, GPR30: Stimulation of Adenylyl Cyclase and cAMP-Mediated Attenuation of the Epidermal Growth Factor Receptor-to-MAPK Signaling Axis

Edward J. Filardo, Jeffrey A. Quinn, A. Raymond Frackelton et al. · Molecular Endocrinology · 2002 · 854 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Tumor promoters block tyrosine-specific phosphorylation of the epidermal growth factor receptor.

B Friedman, A. Raymond Frackelton, Alonzo H. Ross et al. · Proceedings of the National Academy of Sciences · 1984 · 218 citations · Full text

Medicine, Oncology, Pharmacology +17

Evidence for the platelet-derived growth factor-stimulated tyrosine phosphorylation of the platelet-derived growth factor receptor in vivo. Immunopurification using a monoclonal antibody to phosphotyrosine.

A. Raymond Frackelton, Patrice Tremble, L T Williams · Journal of Biological Chemistry · 1984 · 209 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Characterization and use of monoclonal antibodies for isolation of phosphotyrosyl proteins from retrovirus-transformed cells and growth factor-stimulated cells.

A. Raymond Frackelton, Alonzo H. Ross, Herman N. Eisen · Molecular and Cellular Biology · 1983 · 200 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13