The Suppression of Small GTPase Rho Signal Transduction Pathway Inhibits Angiogenesis in Vitro and in Vivo

Isolation of Putative Progenitor Endothelial Cells for Angiogenesis

Takayuki Asahara, Toyoaki Murohara, Alison Sullivan et al. · Science · 1997 · 8.7K citations

Regenerative Medicine, Active Angiogenesis, Utilitarian Angiogenesis +13

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

Catherine D. Nobes, Alan Hall · Cell · 1995 · 4.4K citations · Full text

Actin Stress Fibers, Protein Function, Signal Transduction +13

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

Masayoshi Uehata, Toshimasa Ishizaki, Hiroyuki Satoh et al. · Nature · 1997 · 2.9K citations

Hypertension, Muscle Function, Signal Transduction +11

Role of laminin and basement membrane in the morphological differentiation of human endothelial cells into capillary-like structures.

Yasuo Kubota, Hynda K. Kleinman, George R. Martin et al. · The Journal of Cell Biology · 1988 · 1.2K citations · Full text

Endothelial Cells, Basement Membrane, Cellular Physiology +17

The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase.

T. Ishizaki, Midori Maekawa, Katsuki Fujisawa et al. · The EMBO Journal · 1996 · 884 citations · Full text

Kda Ser/thr Protein, Signal Transduction, Molecular Physiology +12