STUDIES ON BLOOD COAGULATION: THE NATURE AND PROPERTIES OF A PROTEOLYTIC ENZYME DERIVED FROM PLASMA 123

M. H. Kaplan, Henry J. Tagnon, Charles S. Davidson, F. H. L. Taylor

Journal of Clinical Investigation · 1942 · 29 citations · 2 references

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Abstract

In the preceding paper ( 1 ) the preparation, by the action of chloroform on calcium and cell free plasma and subsequent precipitation of the globulins, of a globulin fraction having marked fibrinogenolytic and fibrinolytic properties was described. The present communication describes the chemical nature of these preparations. The preceding paper explains the activity of the chlo- roform plasma preparations on the basis of the presence, in them, of a proteolytic enzyme. The present communication offers evidence substantiating this assumption.

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