Journal of the Chemical Society C Organic · 1970 · 19 citations · 0 references
PharmacyChemistryMedicinal ChemistryNatural Product BiosynthesisOrganic ChemistrySteroid BiochemistryEicosanoid BiosynthesisFlavonoid BiosynthesisOrganic SynthesisPhenylpropanoid BiosynthesisPlant Natural Product BiosynthesisTerpenoid BiosynthesisBiflavonoid BiosynthesisIsoflavonoid Biosynthesis
A novel synthesis of isoflavones from chalcones by use of thallium(III) acetate is reported, and the relationship of this synthesis to the biosynthesis of isoflavones is discussed. The application of this method to the syntheses of three naturally occurring isoflavones, 4′,7-dimethoxyisoflavone (X), milldurone (XIII), and lettadurone (XIV) is described.