Muscarinic receptor heterogeneity in guinea pig intestinal smooth muscle: binding studies with AF-DX 116

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

Binding profile of a novel cardioselective muscarine receptor antagonist, AF-DX 116, to membranes of peripheral tissues and brain in the rat

Rudolf Hammer, E. Giraldo, G.B. Schiavi et al. · Life Sciences · 1986 · 370 citations

Medicine, Neuroscience, Pharmacology +15

Cardioselective profile of AF-DX 116, a muscarine M2 receptor antagonist

Antonio Giachetti, R. Micheletti, E. Montagna · Life Sciences · 1986 · 283 citations

Medicine, Cardiology, Pharmacology +15

STIMULANT ACTIONS OF VOLATILE ANAESTHETICS ON SMOOTH MUSCLE

H P Rang · British Journal of Pharmacology and Chemotherapy · 1964 · 260 citations · Full text

Medicine, Pharmacology, Anesthesia +6

Action of agonists and antagonists at muscarinic receptors present on ileum and atria <i>in vitro</i>

R.U. Clague, Richard M. Eglen, A.C. Strachan et al. · British Journal of Pharmacology · 1985 · 92 citations · Full text

Medicine, Pharmacology, General Pharmacology +13