Convenient two-step stereospecific hydroxy-substitution with retention in β-hydroxy-δ-lactones. 4 ()-heterosubstituted mevinolin and -analogs

Thermal reactions of alkyl N-carbomethoxysulfamate esters

Edward M. Burgess, Harold R. Penton, Edward Alan Taylor · The Journal of Organic Chemistry · 1973 · 378 citations

Chemical Engineering, Engineering, Chemical Analysis +12

Synthetic and biological studies of compactin and related compounds. 4. Total synthesis of (+)-compactin

Terry Rosen, Clayton H. Heathcock · Journal of the American Chemical Society · 1985 · 81 citations

Altmetrics, Molecular Sciences, Biochemistry +14

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 3. 7-(3,5-Disubstituted-[1,1'-biphenyl]-2-yl)-3,5-dihydroxy-6-heptenoic acids and their lactone derivatives

G. E. STOKKER, Alfred W. Alberts, Paul Anderson et al. · Journal of Medicinal Chemistry · 1986 · 68 citations · Full text

Bioorganic Chemistry, Organic Chemistry, Heterocycle Chemistry +16

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 2. Structural modification of 7-(substituted aryl)-3,5-dihydroxy-6-heptenoic acids and their lactone derivatives

William F. Hoffman, Alfred W. Alberts, Edward J. Cragoe et al. · Journal of Medicinal Chemistry · 1986 · 34 citations

Medicinal Chemistry, Biochemistry, Reductase Inhibitors +13

Reactions of Parasorbic Acid. Synthesis of 2-Alkoxy-5,6-dihydro-alpha-pyrans and D,L-Osmunda Lactone.

Kurt Torssell, Madhusudan Tyagi, Christian Pedersen et al. · Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry · 1977 · 23 citations · Full text

Bioorganic Chemistry, Biochemistry, Natural Sciences +7