Inhibition of P-glycoprotein-mediated transport by extracts of and monoterpenoids contained in Zanthoxyli Fructus

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

R. L. Juliano, Victor Ling · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1976 · 3.3K citations

Drug Targeting, Glycosylation, Medicine +12

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells

Chang-jie Chen, Janice E. Chin, Kazumitsu Ueda et al. · Cell · 1986 · 1.9K citations

Antimicrobial Resistance Gene, Multidrug-resistant Human Cells, Health Sciences +11

Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine.

Kazumitsu Ueda, Carol Cardarelli, Michael M. Gottesman et al. · Proceedings of the National Academy of Sciences · 1987 · 1.1K citations · Full text

Full-length Cdna, Immunology, Molecular Biology +16

Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine*

Kenneth S. Lown, Robert R. Mayo, Alan B. Leichtman et al. · Clinical Pharmacology & Therapeutics · 1997 · 683 citations · Full text

Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone.

Kazumitsu Ueda, Noboru Okamura, Midori Hirai et al. · Journal of Biological Chemistry · 1992 · 676 citations · Full text

Cellular Pharmacology, Glucocorticoid, Human P-glycoprotein +16