Concepedia

In Vitro and Pharmacophore-Based Discovery of Novel hPEPT1 Inhibitors

Sean Ekins, Jeffrey S. Johnston, Praveen M. Bahadduri, Vanessa M. D’Souza, Abhijit Ray, Cheng Chang, Peter W. Swaan

Pharmaceutical Research · 2005 · 63 citations · 20 references

DOI

Concepts

References

20

Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

Daniel F. Veber, Stephen R. Johnson, Hung‐Yuan Cheng et al. · Journal of Medicinal Chemistry · 2002 · 8.1K citations

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Valacyclovir: A Substrate for the Intestinal and Renal Peptide Transporters PEPT1 and PEPT2

Malliga E. Ganapathy, Wei Huang, Hong Wang et al. · Biochemical and Biophysical Research Communications · 1998 · 295 citations · Full text

, , +10

Direct Evidence for Peptide Transporter (PepT1)-Mediated Uptake of a Nonpeptide Prodrug, Valacyclovir

Praveen Balimane, Ikumi Tamai, Ailan Guo et al. · Biochemical and Biophysical Research Communications · 1998 · 211 citations · Full text

, , +12

Intestinal Transport of β-Lactam Antibiotics: Analysis of the Affinity at the H+/Peptide Symporter (PEPT1), the Uptake into Caco-2 Cell Monolayers and the Transepithelial Flux

Beate Bretschneider, Matthias Brandsch, Reinhard H.H. Neubert · Pharmaceutical Research · 1999 · 203 citations

, , +17

Pharmacokinetics of Fluvastatin After Single and Multiple Doses in Normal Volunteers

Francis L. S. Tse, James M. Jaffe, August J. Troendle · The Journal of Clinical Pharmacology · 1992 · 174 citations

, , +16