Direct Evidence for Peptide Transporter (PepT1)-Mediated Uptake of a Nonpeptide Prodrug, Valacyclovir

Expression cloning of a mammalian proton-coupled oligopeptide transporter

You-Jun Fei, Yoshikatsu Kanai, Stephan Nußberger et al. · Nature · 1994 · 899 citations

Biochemistry, Proton-coupled Electron Transfer, Proton Transfer +2

Human Intestinal H+/Peptide Cotransporter

Rong Liang, You‐Jun Fei, Puttur D. Prasad et al. · Journal of Biological Chemistry · 1995 · 502 citations · Full text

Absolute bioavailability and metabolic disposition of valaciclovir, the L-valyl ester of acyclovir, following oral administration to humans

J Soul-Lawton, Emma J. Seaber, N.T. On et al. · Antimicrobial Agents and Chemotherapy · 1995 · 313 citations · Full text

Pharmaceutical Science, L-valyl Ester, Plasma Radioactivity +13

Valacyclovir: A Substrate for the Intestinal and Renal Peptide Transporters PEPT1 and PEPT2

Malliga E. Ganapathy, Wei Huang, Hong Wang et al. · Biochemical and Biophysical Research Communications · 1998 · 295 citations · Full text

Molecular Pharmacology, Biochemistry, Medicine +4

Differential Recognition of β-Lactam Antibiotics by Intestinal and Renal Peptide Transporters, PEPT 1 and PEPT 2

Malliga E. Ganapathy, Matthias Brandsch, Puttur D. Prasad et al. · Journal of Biological Chemistry · 1995 · 274 citations · Full text

Cellular Pharmacology, Peptide Science, Antimicrobial Chemotherapy +21