Concepedia

Triapine (3-aminopyridine-2-carboxaldehyde- thiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity

Rick A. Finch, Mao‐Chin Liu, Susan P. Grill, Regina Loomis, Karen M. Vásquez, Yung-Chi Cheng, Alan C. Sartorelli

Biochemical Pharmacology · 2000 · 367 citations · 29 references

DOI

Concepts

References

29

A generalized Wilcoxon test for comparing arbitrarily singly-censored samples

E. A. Gehan · Biometrika · 1965 · 3.4K citations

, , +8

Biochemical strategy of cancer cells and the design of chemotherapy: G. H. A. Clowes Memorial Lecture.

George Weber · PubMed · 1983 · 548 citations

, , +17

Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide.

N S Kwon, Dennis J. Stuehr, C F Nathan · The Journal of Experimental Medicine · 1991 · 430 citations · Full text

, , +13

Ribonucleotide Reductase and Cell Proliferation

Howard L. Elford, Michael Freese, Eugene R. Passamani et al. · Journal of Biological Chemistry · 1970 · 311 citations · Full text

, , +15

A rapid assay for CDP reductase activity in mammalian cell extracts

J.R. Steeper, C D Steuart · Analytical Biochemistry · 1970 · 222 citations

, , +12